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Vasopressin’ me again
I’ve been following the links between blood pressure modulatory hormones and circadian rhythms for a while now — and while it’s a fascinating overall picture, this nut hasn’t been cracked [yet]. A...
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Dopamine and breakfast
While opining on her latest protein-rich breakfast experiment, Jane Plain mentioned ghrelin as an important mediator of the circadian component (more on this below). T.S. Wiley wrote a lot about the...
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Insulin resistance and obesity
Some people believe insulin resistance (IR) causes obesity, and they are not pleased when I say this is actually a controversial topic in the field… “Bill isn’t toeing the company line. Again.” So I...
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LIGHT timing for circadian entrainment
Basically, this much is pretty obvious now: LIGHT and food in the morning + darkness after sunset = proper circadian entrainment. But the how is pretty cool; LIGHT affects different biochemical...
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Gypped by GIP
Dr. Johnson’s recent paper is nothing short of a monster. They did a TON of experiments. Here, I only want to focus on one aspect. The insulin-obesity hypothesis in a nutshell (very oversimplified):...
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Circadian rhythms and prostate cancer
Observations: Incidence of prostate cancer is higher among pilots, flight attendants, and rotating shift workers than the general population (RR as high as 3.0 in some cases!). Circadian rhythms of...
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HANGRY! (part deux)
Effects of diet composition on postprandial energy availability during weight loss maintenance (Walsh et al., 2013) Now, we’re getting somewhere! 3 diets (carbs 10%, 40% or 60%; protein was higher in...
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What or When to Eat
Artificial light at night, crappy sleep, and skipping breakfast are major contributors to poor circadian rhythms. Some bro’s insist WHAT you eat is infinitely more important than WHEN you eat. I beg...
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Mutual influence of sleep and circadian clocks on physiology and cognition
“The 24-hour sleep-wake cycle is one of the most prominent outputs of the circadian clock systems (Heyde et al., 2018)” [Patron link] Sleep disruption and circadian arrhythmia induce metabolic,...
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The carb/insulin model of obesity was tested again, and it fared better this...
Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial (Ebbeling et al., 2018) [Patron link] This is another NuSi study designed to evaluate certain...
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